Results 131 to 140 of about 9,108,761 (329)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Students in rural schools have limited access to advanced mathematics courses [PDF]

open access: yes, 2009
This Carsey brief reveals that students in rural areas and small towns have less access to higher-level mathematics courses than students in urban settings, which results in serious educational consequences, including lower scores on assessment tests and
Graham, Suzanne E.
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Safe Driving for the Mature Adult: Selected Issues [PDF]

open access: yes, 2017
Educational Objectives 1. Examine issues related to aging and driving assessment. 2. Review Virginia’s Mature Drivers Study. 3. Discuss the levels of care for prevention of driving disability and resources available at each level. 4.
Parsio, Rebecca
core   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

An Assessment of Civic Engagement and Educational Attainment [PDF]

open access: yes, 2007
It is well documented that individuals with higher levels of education tend to be more civically engaged. In a two-part study conducted for the Center for Information and Research on Civic Learning and Engagement (CIRCLE), we provide empirical evidence ...
Alberto Davila, Marie T. Mora
core  

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Predicting students\' admission to medical specialty courses based on academic performance and cognitive factors

open access: yesJournal of Medical Education and Development, 2020
Introduction: Nowadays, admission of students for medical specialty courses has faced some challenges. Due to the special importance of the duties and mission of physicians and the necessity of careful selection in their admission, the purpose of this ...
Majid Salimi   +3 more
doaj  

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