Results 81 to 90 of about 9,108,761 (329)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
108 課綱第四學習階段國語文閱讀素養 Development and Validation of an Online
Journal of Research in Education Sciences, 2018 儘管聽、說、讀、寫都是108 學年度預定實施之國語文新課綱的重要元素，然由基本理念可窺知，閱讀能力是新課綱非常重要的關鍵。為發展符合新課綱第四學習階段閱讀素養所需線上評量，本研究目的為建立新課綱第四學習階段國語文素養導向評量發展模式並檢視其成效，從評量架構的建立、文本的挑選或撰寫原則、命題原則等三個方面探討，並分析素養導向試題心理計量特性以支持素養導向評量發展模式的有效性。援用三角檢證法，經由三場評量架構專家會議、20場命題工作坊，本研究取得三向度評量架構與16 項評量指標，建構五項文本的挑選或撰寫原則，
謝佩蓉 Pei-Jung Hsieh
doaj +1 more source
, 2016 This paper examines Information and Communications Technology (ICT) in Nigeria educational assessment system with its emerging challenges. This is inevitable following the globalisation trend which has brought drastic changes in the world of technology ...
O. A. Aworanti
semanticscholar +1 more source
Research quality assessment in education: impossible science, possible art? A response to David Bridges [PDF]
, 2009 Response to keynote presentation by Prof David Bridges on the topic of quality in the Research Assessment Exercise.
Devecchi, Cristina
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Pair interactions in online assessments of collaborative problem solving: case-based portraits
Research and Practice in Technology Enhanced Learning, 2018 This exploratory case study focuses on how pairs of students can build a shared understanding and acquire collaborative problem-solving (CPS) practices during an online assessment of CPS skills, which is seen in the context of the CPS construct, in a ...
Johanna Pöysä-Tarhonen +3 more
doaj +1 more source
Research and Practice in Technology Enhanced Learning, 2021 The current article describes an exploratory study that focussed on joint attention behaviour—the basis of interaction predicting productive collaboration—to better understand collaborative problem solving, particularly its social aspects during remote ...
Johanna Pöysä-Tarhonen +3 more
doaj +1 more source
Open Educational Resources (OER) Project, Fall 2016 Final Dissemination Assessment Report [PDF]
, 2017 ASSESSMENTS TARGETED FOUR CENTRAL AREAS: 1. Textbook Cost Savings 2. Student Perceptions of the OER Materials 3. Student Learning Outcomes 4.
Day, Melissa, Overson, Catherine
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source