Results 51 to 60 of about 1,338,488 (289)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Parental Educational Attainment on Adolescent Educational Development: A Multi-Group Analysis of Chinese Left-Behind and Non-Left-Behind Children

open access: yesBehavioral Sciences
Utilizing data from the China Family Panel Studies (CFPS), this research focuses on the differences and mechanisms of intergenerational educational transmission between left-behind and non-left-behind children using structural equation modeling and multi-
Guilin Xu, Chunhua Fu
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Towards Industrialized Conception and Production of Serious Games [PDF]

open access: yes, 2009
Serious Games (SGs) have experienced a tremendous outburst these last years. Video game companies have been producing fun, user-friendly SGs, but their educational value has yet to be proven.
George, Sébastien   +4 more
core   +4 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

College-Going in the Era of High Expectations: Racial/Ethnic Disparities in College Enrollment, 2006 to 2015

open access: yesSocius, 2021
Adolescents with high educational expectations are more likely to enroll in college. Although most adolescents today report high educational expectations, there remains important racial/ethnic heterogeneity in college enrollment patterns.
Amber D. Villalobos
doaj   +1 more source

Irish pre-service teachers’ expectations for teaching as a career: a snapshot at a time of transition [PDF]

open access: yes, 2017
Recent graduates of teacher education programmes in Ireland are entering their careers at a time characterized by an erosion of teacher autonomy, increased bureaucratic demands, and narrower curriculum specifications. These changes are typical features
Lysaght, Zita   +2 more
core  

The contribution of cultural capital to students' mathematics achievement in medium and high socioeconomic gradient economies [PDF]

open access: yes, 2015
The present study addresses the issue of how different forms of cultural capital may influence children’s mathematics achievement in economies with different socioeconomic gradients.
Atar   +46 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The Interplay Between Families and Schools: Immigrant and Native Differentials in Educational Outcomes [PDF]

open access: yes, 2013
We examine the effects of school context on educational outlooks and outcomes of the children of immigrants, in comparison with natives in Spain, an under-represented case in the international literature and a fast growing immigration destination in ...
Soysal, YN
core  

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