Results 41 to 50 of about 1,352,762 (307)
Large-scale Assessments in EducationBackground Theoretical frameworks excel in conceptualising reading literacy, yet their value hinges on their applicability for real-world purposes, such as assessment.
Kseniia Marcq, Johan Braeken
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Construction of an instrument for the measurement of educational philosophy [PDF]
, 1956 Thesis (M.Ed.)--Boston ...
Callahan, Paul P. +4 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Influences on classification accuracy of exam sets: an example from vocational education and training [PDF]
, 2012 Classification accuracy of single exams is well studied in the educational measurement literature. However, when making important decisions, such as certification decisions, one usually uses several exams: an exam set.
Eggen, T.J.H.M., Hubregtse, M.
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
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Education SciencesThe challenge of designing generative AI (GenAI) tutors that are both pedagogically sound and effective for guided inquiry remains significant. This paper introduces and evaluates a replicable design framework-termed a Pedagogy-to-Prompt Engineering ...
Teng-Chi Lin +2 more
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Education Sciences, 2023 The recent increase in online instruction caused by the 2020 pandemic has reignited the debate over the efficacy of online instruction compared to in-person instruction.
Melissa Larson +3 more
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