Results 51 to 60 of about 1,352,762 (307)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Use of Full Hierarchy Consistency Index to Assess Response Consistency
International Journal of Assessment Tools in Education, 2017 Measurement models need to properly delineate the real aspect of examinees’ response processes for measurement accuracy purposes. To avoid invalid inferences, fit of examinees’ response data to the model is studied through person-fit statistics.
Lokman Akbay, Mustafa Kılınç
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Frontiers in PsychologyIdentifying protective factors that promote academic resilience is vital. Nevertheless, due to the variations in the operationalizations of academic resilience, timeframes, data sources, and employed research methods, it remains unclear whether the ...
Wangqiong Ye, Nani Teig, Sigrid Blömeke
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Invasion of the Christian West by the Tatars (Mongols). A Clash of Civilizations between Frederick II, Gregory IX and the Tatars [PDF]
Золотоордынское обозрение, 2017 Research objectives: The author of this article wants to show how the clash of two different civilizations, until then practically unaware of the other’s existence, the Tatars and the Christian West, undermined the superior and self-confident position ...
Huub Kurstjens
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Measuring is more than assigning numbers [PDF]
, 2010 'Measurement is fundamental to research-related activities in social science (hence this Handbook). In my own field of education research, perhaps the most discussed element of education lies in test scores.
Gorard, Stephen
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Standardized Mean Differences: Not So Standard After All
Campbell Systematic ReviewsMeta‐analyses often use standardized mean differences (SMDs), such as Cohen's d and Hedges' g, to compare treatment effects. However, these SMDs are highly sensitive to the within‐study sample variability used for their standardization, potentially ...
Juyoung Jung, Ariel M. Aloe
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مجله علوم روانشناختی, 2020 Background: Numerous studies have focused on how to build knowledge structure and the factors that affect it. However, research that examines the phenomenon of knowledge constructivism and the construction and validation of the "Mathematical Behavioral ...
Majid Dadashzade +4 more
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