Results 61 to 70 of about 380,132 (314)

Europe as Argument, Value, and Promise? Western European Perspectives on the History of Ukraine in History Curricula and Textbooks

open access: yesZeitschrift für Ostmitteleuropa-Forschung
This article takes a comparative perspective on the question of how the history of Ukraine is represented in recent history textbooks of Germany, France, Italy, Spain, and the UK in a categorical relation to Europe.
Steffen Sammler, Marcus Otto
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Commonwealth Educational Media Centre for Asia (CEMCA) Annual Report: 2019-2020

open access: yes, 2020
Commonwealth Educational Media Centre for Asia (CEMCA) Annual Report for 2019 ...

core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Local Disaster Risk Maps as an Educational Medium for Productive Age Groups in Disaster-Prone Areas [PDF]

open access: yesSHS Web of Conferences
Indonesia is a country with the longest coastline in Asia, this creates a high level of risk of hydrometeorological disasters such as floods, tsunamis, extreme waves and abrasion.
Ayu Angelina Indriani Diah   +7 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Media and Education [PDF]

open access: yes
In this volume, we explore critical questions about Norway's hidden history of racism and its implications today. Why has Norway largely overlooked its role in the transatlantic slave trade? How do media representations shape public perceptions of race? What can education do to confront and dismantle systemic racism?
Kuyini Alhassan, Abdul-Razak   +2 more
openaire   +2 more sources

Commonwealth Educational Media Centre for Asia (CEMCA)

open access: yes, 2012
The Commonwealth Educational Media Centre for Asia (CEMCA) serves as the regional unit of the Commonwealth of Learning. CEMCA promotes the meaningful, relevant and appropriate use of ICTs to serve the educational and training needs of Commonwealth member

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Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

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