Results 71 to 80 of about 12,528,727 (304)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Educational Needs Assessment of Diabetic Pregnant Mothers in Meshgin Health Centers in 2018
Background & objectives: Gestational diabetes is one of the most common medical problems during pregnancy, which has many negative consequences for mother and fetus.
Marziyeh Avazeh +4 more
doaj
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Educational assesment in training of competent doctors in ukraine: problems and their decision
In article deals with the problem of the use of educational assessment in the training of future doctors in Ukraine. The key role of educational assessment in the improvement of the quality of higher medical education was defined.
Kulbashna Yaroslava, Astapenko Olena
doaj +1 more source
Exploring the process of educational change in English medium senior secondary school Assessment in Vanuatu [PDF]
Educational change is ongoing. It is generally aimed at improving teaching and learning, but usually comes with challenges. Scholars have devoted a great deal of research to minimise the challenges faced by implementers of change, but there is no one ...
Tarosa, Gayleen Harrison
core
Method Effects and the Need for Cognition Scale [PDF]
Individual differences in the need for cognition are typically assessed using the 18-item Need for cognition scale (NCS) developed by Cacioppo and Petty (1982).
Ni Chuinneagain, S +5 more
core +4 more sources
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Need Assessment For Sex Educational Amongst The School Children
Research question: Will the sex education given to the students help in STD prevention, population control and in their future sex life. Hypothesis : In order to have a successful school based sex education programme, it is necessary to involve the ...
Thakor H.G, Kumar P
doaj
Promoting emotional, social and civic competencies: Educational policies in Spain [PDF]
This article analyzes Spain’s educational policies in terms of emotional, social, and civic competencies. The need to teach these competencies at school is justified socially and pedagogically, and the way in which these competencies are implemented in
Romero Pérez, Clara +1 more
core +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source

