Results 81 to 90 of about 12,528,727 (304)

Need supportive teaching in practice: A narrative analysis in schools with contrasting educational approaches [PDF]

open access: yes, 2015
Research on self-determination theory (SDT) has shown that positive learning outcomes accrue in classrooms that support students’ needs for autonomy, competence, and relatedness.
Stroet, Kim   +9 more
core   +2 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Legal and Bioethical Educational Module in Saudi Board of Emergency Medicine: A Qualitative Need Assessment”

open access: yesAdvances in Medical Education and Practice, 2023
Badriah Alruwaili,1,2 Nouf S Alharbi,2 Noof K Albaz2 1Department of Emergency Medicine, King Abdullah bin Abdulaziz University Hospital, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia; 2Department of Medical Education, College of ...
Alruwaili B, Alharbi NS, Albaz NK
doaj  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Arabic Language Education Assessment through International Experiences: A Comparative Analysis

open access: yesJournal of Arabic Language Learning and Teaching
This study explores the evolving role of educational assessment in enhancing the learning process, shifting from merely measuring academic achievement to a comprehensive tool for evaluating all educational aspects.
Nadia ElMeftahy
doaj   +1 more source

Changing Assessment Practice: Process, Principles and Standards [PDF]

open access: yes, 2008
This is a brief account of what has been learned during the Analysis and Review of Innovations in Assessment (ARIA) project about how changes in assessment practice may be brought about most eff ectively.
Gardner, John   +3 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Learning Needs Assessment in Bachelor of Nursing: a Qualitative Research [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2005
Introduction: One of the most important components of educational technology is educational needs assessment. This study tried to answer the question of, what the real needs of bachelor nursing students based on their experience?
A Zareiyan Jahromi, F Ahmadi
doaj  

Quality assessment by science teachers: Five focus areas [PDF]

open access: yes, 2013
In order to teach science well, science teachers need to know what to focus on in order to ensure their assessment of student learning is meaningful and useful for the students’ on going learning and development.
Edwards, Frances
core   +1 more source

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