Results 61 to 70 of about 3,340,934 (313)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
La fiabilité : une voie vers l’équité ?
Revue Internationale d’Éducation de Sèvres, 2020 There is no shortage of good ideas and innovations in the education field. And yet schooling remains grossly unable to meet the needs of all students, particularly students of colour and poor students.
Louis M. Gomez +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Virtual Conductor for String Quartet Practice [PDF]
, 2013 This paper presents a system that emulates an ensemble conductor for string quartets. This application has been developed as a support tool for individual and group practice, so that users of any age range can use it to further hone their skills, both ...
Barbancho-Pérez, Ana María +4 more
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Pro-PosiçõesResumo Este artigo apresenta pesquisa sobre práticas e interações em creches e pré-escolas, identificando convergências e divergências. O referencial teórico se baseia na filosofia do diálogo de Martin Buber, e o metodológico, na sociologia da infância ...
Sonia Kramer +4 more
doaj +1 more source
Cadernos de Pesquisa, 2012 Este artigo apresenta dados de pesquisa sobre a organização escolar e curricular de escolas primárias na colônia catarinense Hansa, fundada em 1897. Foi baseado na análise de documentos da Companhia Colonizadora Hamburguesa.
Ademir Valdir dos Santos
doaj +1 more source
Counselling immigrant adults at an educational institution [PDF]
, 2005 The principle of promoting free mobility of citizens has been written into European educational policies. Additionally, the philosophy of educational equality has been clearly included into the educational regulation of most European countries ...
Clayton, P. +2 more
core
Administering LAAIs: an education and training workshop [PDF]
, 2013 This is the second of two articles that focus on the inter-collaborative work, between education and practice, to enhance theoretical and practical delivery for mental health nurses when administrating long-acting antipsychotic injections (LAAIs).
Covill, Carl +3 more
core +1 more source