Results 61 to 70 of about 803,592 (314)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

PERSONAL AND PROFESSIONAL DEVELOPMENT OF FUTURE EDUCATORS IN THE PROCESS OF EDUCATIONAL PRACTICES

open access: yesНеперервна професійна освіта: теорія та практика, 2020
The article highlights the features of content and technology support of personal and professional development of future teachers in the process of educational practices. Abovementioned ideas are presented here in an anthropological dimension.
Hanna Ivaniuk   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Educação e colonização no Brasil: as escolas étnicas alemãs Education and colonization in Brazil: german ethnic schools

open access: yesCadernos de Pesquisa, 2012
Este artigo apresenta dados de pesquisa sobre a organização escolar e curricular de escolas primárias na colônia catarinense Hansa, fundada em 1897. Foi baseado na análise de documentos da Companhia Colonizadora Hamburguesa.
Ademir Valdir dos Santos
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The effect of educational leadership on organizational variables: a meta–analysis study in the sample of Turkey

open access: yes, 2016
The purpose of this study is to test the effect of educational leadership on some organizational variables using meta–analysis method. In this context, the results of independent researches were merged together and the hypotheses created within the scope
Çoğaltay, N.   +3 more
core   +1 more source

La fiabilité : une voie vers l’équité ?

open access: yesRevue Internationale d’Éducation de Sèvres, 2020
There is no shortage of good ideas and innovations in the education field. And yet schooling remains grossly unable to meet the needs of all students, particularly students of colour and poor students.
Louis M. Gomez   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Inclusive Educational System and Practice in Japan

open access: yes, 2022
This chapter explores the distinctive way in which the dual educational system in Japan has extended its special education services to create opportunities for more inclusive practice within mainstream schools. Legislation has promoted top-down political
Wakui, Megumi   +3 more
core   +1 more source

Encontros e desencontros de crianças e adultos na Educação Infantil: uma análise a partir de Martin Buber

open access: yesPro-Posições
Resumo Este artigo apresenta pesquisa sobre práticas e interações em creches e pré-escolas, identificando convergências e divergências. O referencial teórico se baseia na filosofia do diálogo de Martin Buber, e o metodológico, na sociologia da infância ...
Sonia Kramer   +4 more
doaj   +1 more source

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