SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Dementia diagnosis in primary care: testing an educational program in Oregon. [PDF]
Lindauer A +7 more
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
The impact of an educational program on the electronic waste management knowledge and practices of dental interns: an interventional study. [PDF]
Galal RS +4 more
europepmc +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Implementation and Evaluation of a Pediatric Pain Assessment Educational Program (PPAEP) for Nurses in a Resource-Limited Setting: A Pilot Study. [PDF]
Kusi Amponsah A +12 more
europepmc +1 more source
Compilation and development of K-6 aerospace materials for implementation in NASA spacelink electronic information system [PDF]
Spacelink is an electronic information service to be operated by the Marshall Space Flight Center. It will provide NASA news and educational resources including software programs that can be accessed by anyone with a computer and modem.
Blake, Jean A.
core +1 more source
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Prevalence and Impact of Simulation Substitution on Paramedic Educational Program Success: A National Examination. [PDF]
Salhi HE +7 more
europepmc +1 more source

