Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gifted and talented education in Aotearoa New Zealand : a primary school perspective : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education at Massey University, Manawatū, New Zealand [PDF]
This research explores the state of gifted and talented education in New Zealand following the 2008 change in government and consequent shift in educational priorities. This case study examines the provision of gifted and talented education in a full, co-
Wallace, Jami Kimbrough
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Educational outcomes in extremely preterm children : neuropsychological correlates and predictors of attainment [PDF]
This study assessed the impact of extremely preterm birth on academic attainment at 11 years of age, investigated neuropsychological antecedents of attainment in reading and mathematics, and examined early predictors of educational outcomes.
Achenbach T. M. +18 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
EXTENSION EDUCATORS' SUPPLY OF RISK MANAGEMENT TRAINING TO FARMERS [PDF]
A univariate Tobit model of extension educators' provision of risk management educational training was conducted in Mississippi, Texas, Indiana, and Nebraska.
Baquet, Alan E. +5 more
core +1 more source
The education of travelling children [PDF]
Summary This report summarises the evidence from a series of visits conducted by Ofsted. HMI undertook these visits to examine the quality of the educational opportunities and provision for Travelling children and the extent to which they succeeded in ...
core
Universities and community-based research in developing countries: community voice and educational provision in rural Tanzania [PDF]
The main focus of recent research on the community engagement role of universities has been in developed countries, generally in towns and cities and usually conducted from the perspectives of universities rather than the communities with which they ...
Adler P. S. +49 more
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
What are Bicultural Psychological Services? [PDF]
The present paper is intended to stimulate discussion on the development of bicultural psychological services in Aotearoa/New Zealand, focusing primarily on services provided by psychologists trained in tertiary educational institutions.
Thomas, David R.
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

