Results 101 to 110 of about 424,348 (309)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Current status of self-assessment and training needs among primary-level infectious disease prevention and control personnel in Xinjiang Uygur Autonomous Region: a cross-sectional survey, 2025

open access: yesZhongguo gonggong weisheng
ObjectiveTo investigate the current status of competency and training needs among primary-level infectious disease prevention and control personnel in Xinjiang Uygur Autonomous Region, providing a scientific basis for further exploring training models to
Xinyu HU   +5 more
doaj   +1 more source

The nature and outcomes of PGCE Plus as a model for teacher professional development [PDF]

open access: yes
The present study examines an innovative attempt to address national priorities with regard to subject (mathematics and science) and the needs of gifted and talented pupils. The initiative, PGCE Plus, was at the transition from initial qualifications and
Arweck, Elisabeth   +3 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Education practices: research-action with nurses of Family Health Strategy

open access: yesRevista Brasileira de Enfermagem
Objective: to identify the factors that determine the implementation of educational practices of health promotion and to construct proposals to implement the educational actions of the nurses of the Family Health Units (FHU).
Carlos Frank Viga Ramos   +4 more
doaj   +1 more source

Recruiting High Quality Teachers [PDF]

open access: yes
Bildungspolitik, Qualifikation, Lehrkräfte, Hochqualifizierte Arbeitskräfte, Pädagogik, Erwerbsstatus, Gehalt, Educational policy, Occupational qualification, Teaching personnel, Highly skilled labour, Education sciences, Occupational status ...
Peter Dolton
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

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