Results 81 to 90 of about 424,348 (309)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

DEMOGRAPHIC FACTORS AND LABOR TURNOVER IN HONDA MANUFACTURING LIMITED OTA, OGUN STATE NIGERIA [PDF]

open access: yesBusiness Excellence and Management, 2020
This study examines the effect of demographic factors on labor turnover in Honda Manufacturing Company. The study examines three objectives which are to determine the effect of age on labor turnover, ascertain the influence of work experience on labor ...
Bashiru Akande Bello   +2 more
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

A Simple Model of Educational Production [PDF]

open access: yes
There is a large body of literature on the effect of educational resources on student performance, such as teacher qualification, class size, and physical resources in school.
Jaag, Christian
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Success Despite Starting out at a Disadvantage: What Helps Second-Generation Migrants in France and Germany? [PDF]

open access: yes
The educational and employment trajectories of migrant children in France and Germany are extremely diverse. The few successful ones dominate the public eye.
Ariane Jossin   +3 more
core  

work program of the course Football, mini-football and Methods of Teaching [PDF]

open access: yes, 2014
Програма визначає обсяги знань, які повинен опанувати бакалавр відповідно до вимог освітньо-кваліфікаційної характеристики, алгоритму вивчення навчального матеріалу дисципліниThe program determines the volume of knowledge that should master bachelor ...
Косік, Микола Сергійович
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

State of Professional Preparation of Future Physical Training Teachers to Teach Swimming at Children’s Holiday Camps

open access: yesPhysical Education Theory and Methodology, 2016
The paper reviews the state of professional preparation of future physical education teachers relying on the comparison of the fundamental documents that shape the professional competence of a swimming instrucror at children’s holiday camps.
C. М. Клімакова
doaj   +1 more source

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