Results 101 to 110 of about 635,376 (265)

School-based management: Catalyzing stakeholder engagement for enhanced educational quality in Bekasi

open access: yesJournal of Education and Health Promotion
BACKGROUND: Enhancing educational quality through participatory governance is a national priority in Indonesia’s primary education sector. School-Based Management (SBM) provides a framework for decentralizing decision-making and strengthening ...
Ade Mutiarawati   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Internal Evaluation of Residency Training Programs for Selected Specialized Groups at Guilan University of Medical Sciences: The Essential Need for Monitoring Specialized Training Courses [PDF]

open access: yesPizhūhish dar Āmūzish-i ̒ulūm-i Pizishkī
In the medical education environment, ensuring and continuously improving quality has become an indispensable necessity. This technical note examines the internal evaluation process of residency training programs at the school of medicine of Guilan ...
Jalal Kheirkhah   +5 more
doaj  

Spatial Variation in Educational Quality in Colombia Based on the Phenomena of Agglomeration and Academic Segregation. [PDF]

open access: yesEur J Investig Health Psychol Educ, 2022
Castro-Aristizabal G   +4 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Perception of Social and Educational Quality of Life of Minors Diagnosed with Rare Diseases: A Systematic Review and Meta-Analysis. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Coca JR   +4 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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