Results 111 to 120 of about 635,376 (265)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Enfoque de Gestión Universitaria en la vinculación educativa comunitaria

open access: yesCiencia UNEMI, 2011
The increase in population density and the constant difficulties that exist in low-income urban areas means that the financial resources which the autonomous decentralized municipal government has de- signated for dealing with "invasions" of plots of ...
Orozco-Hernández, Jaime   +1 more
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

QUALITY OF EDUCATION IS THE QUALITY OF LIFE

open access: yes
The article provides a brief definition of education in the era of globalization, highlighting the role of education quality. It emphasizes that the ecological, socio-political, and economic problems and crises arising during globalization, as well as their solutions, are linked to the quality of education.
openaire   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Evaluation of Effective factor on the Education Performance of Medical physics group

open access: yesآموزش پزشکی, 2018
BACKGROUND AND OBJECTIVE: Improving the quality of education is done based on a method or model at each university. One of the methods and indicators for assessing educational quality is internal evaluation and each university will be able to plan and ...
Majid Jadidi   +3 more
doaj  

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