Results 61 to 70 of about 2,551,258 (350)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Engineering education standards

open access: yesYearbook Telecommunications, 2022
Professions such as engineering, architecture, medicine and others are related to work that directly affects the life of society. The engineering profession is rapidly changing and extremely responsible, and requires rigorous assessment of the competence and commitment of engineering professionals.
openaire   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The Measurement of Educational Inequality: Achievement and Opportunity [PDF]

open access: yes
This paper proposes two related measures of educational inequality: one for educational achievement and another for educational opportunity. The former is the simple variance (or standard deviation) of test scores.
Ferreira, Francisco H.G.   +1 more
core   +3 more sources

Philosophical Competencies: What Should They Be?

open access: yesФілософія освіти, 2016
The article discusses the system of general and specific competences in the educational standard of philosophy. The basic principles of developing a set of competencies. Define their relationship with the Tuning project.
Sergii Proleiev
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

An Analysis of Rx for Discovery Reading for Elementary Students Below Grade Level in Reading [PDF]

open access: yes, 2009
Rx for Discovery Reading® is an intervention developed by the National Institute for Learning Development to impact the reading abilities of students below grade level in reading.
Stanley, Susan Kay
core   +1 more source

Finding your way into an open online learning community [PDF]

open access: yes, 2008
Making educational materials freely available on the web is not only a noble enterprise, but also fits the call of helping people to become lifelong learners; a call which gets louder and louder every day.
John van der Baaren   +3 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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