Results 71 to 80 of about 2,576,100 (300)
, 2013 This Deliverable gives a detailed description of the comprehensive training programme and of the open educational content that the University of Padua has accomplished up to now for the project "Linked Heritage: Coordination of standard and technologies ...
Bianchi , Elena +2 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Developing professional competencies of students of the faculty of physical education and sports [PDF]
Физическое воспитание и студенческий спортRelevance of the study is justified by the specifics of training senior students in the field 44.03.01 “Pedagogical Education” with a specialization in “Physical Culture”, which is related in our research to the amount of contact ...
Vodolagina, Irina Yu. +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The interaction of science and higher education in the higher education system of the Republic of Moldova [PDF]
Eastern European Journal of Regional Studies, 2015 This article analyses the situation in the sphere of science and higher education integration in the Republic of Moldova, produced within the international project FKTBUM "Fostering the knowledge triangle in Belarus, Ukraine and Moldova".
Cristina COSCIUG, Elena SIMCIUC
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Technology Support of Professional Personnel of Developing Economic Systems
Управленческое консультирование, 2018 The article presents the main proposals in the present draft of the economic-mathematical research on the development of technologies of staffing in priority directions of development of economic systems of Federal and regional levels (hereinafter — the ...
V. A. Kurzenev +3 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source