Results 41 to 50 of about 291,519 (307)

Kulturelle Deutungsmuster interkulturellen Handelns. Bedeutung für die Grundlagenforschung und Anwendung im DaF-Bereich

open access: yesActa Universitatis Carolinae Philologica, 2018
This contribution analyzes the cultural interpretation patterns of intercultural action. It focuses first of all on the revision of the European Union’s language policy and the concept of intercultural competence used in European regulations.
Barbara Heinsch
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Competence – based approach in training masters for water management

open access: yesВодное хозяйство России: проблемы, технологии, управление, 2022
Objectives of this work has been determined by the world-wide water resources quality deterioration and increase of the signifi cance of experts capable not only of designing and building of the industrial/drinking water treatment systems, waste water ...
Olga Naschetnikova   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Standards for educational and psychological testing

open access: yes, 2014
Developed jointly by the American Educational Research Association, American Psychological Association, and the National Council on Measurement in Education, Standards for Educational and Psychological Testing (Revised 2014) addresses professional and ...
American Educational Research Association
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The Higher Accounting Education in Primorsky Territory: History and New Horizons of Development

open access: yesУчёт. Анализ. Аудит, 2019
This article is devoted to the history of development of the higher accounting education in Primorsky Territory: starting from the creation of the Vladivostok branch of the Moscow institute of a national economy of G.V.
Olga G. Zhitlukhina   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

IMPLEMENTATION OF FEDERAL EDUCATIONAL STANDARDS AND INTERNATIONAL STANDARDS FOR DESIGNING, PERFORMING AND QUALITY EVALUATION OF ENGINEERING EDUCATIONAL PROGRAMMES

open access: yesВысшее образование в России, 2016
The paper observes the comparative study of the requirements of a new version of Federal Educational Standards (known as FES 3+), international CDIO Standards and professional accreditation criteria of the Association for Engineering Education of Russia (
Alexander I. Chuchalin   +1 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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