Results 61 to 70 of about 291,519 (307)

Role of standards in quality management of electronic educational resources [PDF]

open access: yes, 2013
Представлені результати з аналізу ролі стандартів в системі управління якістю електронних освітніх ресурсів (ЕОР) університету. Описані вимоги та специфікації, методи та технології використання стандартів для визначення критеріїв, організації та ...
Кравцов, Г.М.
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The Impact of Grading Standards on Student Achievement, Educational Attainment, and Entry-Level Earnings [PDF]

open access: yes
Despite recent theoretical work and proposals from educational reformers, there is little empirical work on the effects of higher grading standards.
Julian R. Betts, Jeff Grogger
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Constantly weighing the pig will not make it grow: do teachers teach assessment tests or the curriculum?

open access: yesPerspectives in Education, 2014
For a number of years now, South Africa, like many other countries, has been debating a major paradigm shift in education, a shift from learning and teaching, which focused primarily on content to learning and teaching focused on outcomes.
Michael le Cordeur
doaj   +3 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Defying decay: a strategy to enforce infrastructure standards in rural schools within the Eastern Cape, South Africa

open access: yesFrontiers in Built Environment
The Eastern Cape Department of Education (ECDoE) in South Africa faces significant infrastructure challenges in rural schools, including inadequate funding, poor maintenance, and a shortage of essential facilities.
Buyisiwe Ndungane   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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