Results 71 to 80 of about 2,669,245 (360)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

O trabalho infantil doméstico e o processo de escolarização Domestic child labour and the scholarship process

open access: yesPsicologia & Sociedade, 2011
O trabalho versa sobre uma pesquisa na qual se buscou verificar a relação entre o Trabalho Infantil Doméstico e o processo de escolarização. Participaram 100 sujeitos de ambos os sexos, na faixa compreendida entre os 07 e 18 anos de idade.
Maria de Fátima Pereira Alberto   +4 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Gender differences in social mortality differentials in Switzerland (1990-2005) [PDF]

open access: yes
Using data from the 1990 and 2000 Swiss Federal Censuses linked to the death records of the years 1990-1995 and 2000-2005, this paper investigates gender differences in mortality differentials by level of educational achievement and by marital status. In
Reto Schumacher, Sarah Vilpert
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Changing trends in the prevalence of blindness and visual impairment in a rural district of India: Systematic observations over a decade

open access: yesIndian Journal of Ophthalmology, 2012
Context : Globally, limited data are available on changing trends of blindness from a single region. Aims : To report the changing trends in the prevalence of blindness, visual impairment (VI), and visual outcomes of cataract surgery in a rural district ...
Rohit C Khanna   +5 more
doaj   +1 more source

Development of a Kannada Version of the Newest Vital Sign Health Literacy Tool and Assessment of Health Literacy in Patients with Tuberculosis: A Cross-Sectional Study at a District Tuberculosis Treatment Centre [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2021
Background: Ensuring that the patient comprehends and correctly implements the physician's/health care worker's instructions is crucial in the treatment of Tuberculosis (TB). Our study aimed to assess the Heath Literacy (HL) of patients with TB using the
Arjun Manel Nayak   +9 more
doaj  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Critical issues in implementing low vision care in the Asia-Pacific region

open access: yesIndian Journal of Ophthalmology, 2012
Two-thirds of the world′s population with low vision resides in the Asia-Pacific region. Provision of comprehensive low vision services is important to improve vision-related quality of life (QoL) for people with this condition.
Peggy Pei-Chia Chiang   +3 more
doaj   +1 more source

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