Results 101 to 110 of about 10,897,160 (400)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The social construction of educational technology through the use of proprietary software [PDF]

, 2010
Major strands of science and technology studies (STS) in recent decades have been the 'social shaping of technology' (SST) and 'social construction of technology' (SCOT) movements, whose adherents maintain that technological systems are determined just ...
Bissell, Christopher
core  

EDITORIAL.TECHNOLOGY AS A SUPPORT TO TRADITIONAL ASSESSMENT PRACTICES [PDF]

, 2018
Assessment in education is under pressure to change. Some drivers for change result from new ways of thinking about assessment and its educational purposes. Other drivers are external and are the result of wider changes in society.
Grion, Valentina, Nicol, DAVID JOHN, Serbati, Anna   +2 more
core   +2 more sources

New educational technology in university

Polylinguality and Transcultural Practices, 2014
The article is devoted to consideration of the two new educational technologies at the University. This quantization of texts and the supertest.
V S Avanesov
doaj  

What in the world is educational technology? Rethinking the field from the perspective of the philosophy of technology

Journal of Educational Media, 2020
Technology has been an important influence on the development of education. However, very little research in Educational Technology considers this history, and even less questions it.
Tao An, M. Oliver
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

A Way to Learn How to Design Educational Software [PDF]

Journal of Systemics, Cybernetics and Informatics, 2004
The improvement in the quality of instructional process stimulates the development of active teaching methods based on "learning by doing" principles. This paper shows an experience developed on educational informatics course to engineering instructors ...
Dalia M. Gil, Miguel A. Garay
doaj  

Philosophy of Technology Assumptions in Educational Technology Leadership [PDF]

, 2017
A qualitative study using grounded theory methods was conducted to (a) examine what philosophy of technology assumptions are present in the thinking of K-12 technology leaders, (b) investigate how the assumptions may influence technology decision making,
Webster, Mark David
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

THE Sociology of Educational Technology

Sakarya Üniversitesi Eğitim Fakültesi Dergisi, 2014
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Ahmet Eskicumalı
doaj