Results 101 to 110 of about 601,336 (297)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Critique [of Institutional Racism] [PDF]

, 1982
“The complex of concepts which western peoples use to process data and make decisions are the ultimate enemy of minorities. . . .” As an educator, and especially as one involved in educating journalists, I found myself drawn to Deloria’s ...
Luebke, Barbara F.
core   +1 more source

Cassandra’s prophecy: education, education, education [PDF]

Reproductive BioMedicine Online, 2013
This is a commentary on the personal account of Jane Everywoman. It reflects on her experiences and thoughts. The author adds context from her own work with the Progress Educational Trust, the Daisy Network Premature Menopause Support Group and the National Infertility Awareness Campaign.
openaire   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Becoming a teacher educator : guidelines for induction : 2nd edition [PDF]

, 2011
The first edition of these guidelines was published in 2007. Since that date it has been used to support the induction of new teacher educators in the UK and beyond.
Boyd, Pete, Harris, Kim, Murray, Jean
core   +1 more source

Educators’ experiences and coping strategies in response to learner violence in Mopani district, Limpopo

The Journal for Transdisciplinary Research in Southern Africa
Violence in school settings can induce emotional and psychological distress in educators, resulting in emotional exhaustion and difficulty focusing on daily duties.
Thobile P. Badimo, Itumeleng M. Masisi
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Lifelong Learning Through the Prism of Educators

Revija za Elementarno Izobraževanje
Continuous professional development and training represent not only choices, but also an obligation and responsibility for every single educator. The aim of the research was to investigate the attitudes of educators working in kindergartens in seven ...
Korana Lisjak, Anita Zovko
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

The Other Costs of Trauma: Educator Compassion Fatigue [PDF]

, 2016
In this column, Dr. Oliver tackles the topic of compassion fatigue in educators and reminds those working with children impacted by trauma to recognize their own ...
Oliver, Brandie M.
core   +1 more source