Results 61 to 70 of about 151,290 (231)

Behind the case files: The psychological toll of investigating sexual and corporal abuse in South African schools

International Journal of Studies in Psychology
This study explored the psychological toll experienced by South African Council for Educators (SACE) investigators responsible for handling cases of sexual and corporal abuse in schools.
Phumuzani Mpofu, Simangele Mayisela, Tuzana Sophethe, Ella Mokgalane   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

On the Determination of Meshed Distribution Networks Operational Points after Reinforcement

Applied Sciences, 2019
This paper proposes a calculation algorithm that creates operational points and evaluates the performance of distribution lines after reinforcement. The operational points of the line are probabilistically determined using Monte Carlo simulation for ...
Vasiliki Vita, Stavros Lazarou, Christos A. Christodoulou, George Seritan   +3 more
doaj   +1 more source

Cassandra’s prophecy: education, education, education [PDF]

Reproductive BioMedicine Online, 2013
This is a commentary on the personal account of Jane Everywoman. It reflects on her experiences and thoughts. The author adds context from her own work with the Progress Educational Trust, the Daisy Network Premature Menopause Support Group and the National Infertility Awareness Campaign.
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

On the Computation of the Voltage Distribution along the Non-Linear Resistor of Gapless Metal Oxide Surge Arresters

Energies, 2018
The voltage distribution along the non-linear resistance of metal oxide surges is of great importance for their proper operation, since the non-uniform potential distribution results in higher thermal stresses of the varistor discs near the high voltage ...
Christos A. Christodoulou, Vasiliki Vita, Valeri Mladenov, Lambros Ekonomou   +3 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Enhancing Academic Writing Proficiency among English as a Second Language Users at the Undergraduate Level: A Comparative Analysis of Student-Lecturer Perspectives and Strategies [PDF]

Research and Education
Academic writing is a pivotal concern in the tertiary phase of education, yet with a great deal of drawbacks and challenges. The current study investigates academic writing-related challenges and possible mechanisms to overcome them.
Rashmika Lekamge, Jenan Rajavarathan
doaj   +1 more source