Results 111 to 120 of about 243,062 (285)
The coordination between regional ecological and economic development has become a crucial topic in current environmental and development research due to the establishment of sustainable development goals and the acceleration of urbanization.
Shuxiang Li, Shuhua Ma
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Managing trade but mangling the consumer: Reflections on the EEC's and West Germany's experience with the MFA [PDF]
The paper begins with a brief overview of the developments leading up to the MFA and the role played by the European Economic Community (EEC), the largest market in the world for textiles and clothing.
Spinanger, Dean, Zietz, Joachim
core
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Boron nitride (BN) ceramic is an important support material in aerospace, arc discharge devices, and vacuum electronics. The electron emission properties of BN surfaces are of significance among various space applications.
Yuqing Gu, Juannan Li, Dan Wang
doaj +1 more source
The European regulatory system. Organic farming and production [PDF]
The European Union is the biggest consumer market for organic produce. Consequently, its regulatory system on organic farming is of special interest, not just to Europeans dealing with organic products, but also to those who target their product to this ...
Wilbois, Klaus-Peter
core
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Trade Shocks and Industrial Location: the Impact of EEC Accession on the UK [PDF]
This paper combines detailed production data (from the ARD) with international trade data by port to examine the impact of accession to the EEC on the location of UK manufacturing. The paper has two main objectives.
Henry Overman, L. Alan Winters
core

