Results 111 to 120 of about 243,062 (285)

A Quantitative Analysis on the Coordination of Regional Ecological and Economic Development Based on the Ecosystem Service Evaluation

open access: yesLand
The coordination between regional ecological and economic development has become a crucial topic in current environmental and development research due to the establishment of sustainable development goals and the acceleration of urbanization.
Shuxiang Li, Shuhua Ma
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Managing trade but mangling the consumer: Reflections on the EEC's and West Germany's experience with the MFA [PDF]

open access: yes
The paper begins with a brief overview of the developments leading up to the MFA and the role played by the European Economic Community (EEC), the largest market in the world for textiles and clothing.
Spinanger, Dean, Zietz, Joachim
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Investigation on the Electron Emission Regularity of Sputtered Boron Nitride Thin Films and Microstructured Array Surfaces

open access: yesInorganics
Boron nitride (BN) ceramic is an important support material in aerospace, arc discharge devices, and vacuum electronics. The electron emission properties of BN surfaces are of significance among various space applications.
Yuqing Gu, Juannan Li, Dan Wang
doaj   +1 more source

The European regulatory system. Organic farming and production [PDF]

open access: yes, 2001
The European Union is the biggest consumer market for organic produce. Consequently, its regulatory system on organic farming is of special interest, not just to Europeans dealing with organic products, but also to those who target their product to this ...
Wilbois, Klaus-Peter
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Trade Shocks and Industrial Location: the Impact of EEC Accession on the UK [PDF]

open access: yes
This paper combines detailed production data (from the ARD) with international trade data by port to examine the impact of accession to the EEC on the location of UK manufacturing. The paper has two main objectives.
Henry Overman, L. Alan Winters
core  

Home - About - Disclaimer - Privacy