Results 61 to 70 of about 7,423 (270)
Рациональная фармакотерапия в кардиологии, 2018 Aim. To study the erythrocyte electric charge (EEC) in patients with metabolic syndrome (MS).Material and methods. 112 patients (mean age 61.4±7.2 years) with MS (average duration of MS 8.7±5.2 years) were examined.
V. I. Podzolkov +5 more
doaj +1 more source
Argon laser surgery of mucous membranes papillomatosis in EEC syndrome and Goltz syndrome [PDF]
, 1991 This article describes successful results after argon laser surgery of verrucous and papillomatous lesions on the mucous membranes of the lips in two patients; the first with the EEC syndrome and the second with the Goltz syndrome.
Hernandez, D. A., Pasyk, Krystyna A.
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Indian Journal of Paediatric DermatologyEctrodactyly–ectodermal dysplasia–cleft lip/palate (EEC) syndrome is a rare genetic disorder that affects ectodermal derived structures, including teeth, nails, hair, and sweat glands along with ectrodactyly and clefting of lip/palate.
Shivani Ranjan, Neha Akhoon
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Ectrodactyly: A rare anomaly of limbs
Journal of Dr. NTR University of Health Sciences, 2015 Ectrodactyly refers to the congenital limb malformation, characterized by a deep median cleft of the hand and/or foot due to the absence of central rays.
Nirmala SVSG +4 more
doaj +1 more source
TP63‐mutation as a cause of prenatal lethal multicystic dysplastic kidneys
Molecular Genetics & Genomic Medicine, 2020 Background Ectrodactyly‐ectodermal dysplasia‐clefting syndrome 3 (EEC) is one of the six overlapping syndromes caused by mutations in the tumor protein p63 gene (TP63). EEC is suspected when patients have cleft hands or feet, polydactyly, and syndactyly,
Isabel Friedmann +4 more
doaj +1 more source
TP63 mutation mapping information in TP63 mutation-associated syndromes
Advances in Oral and Maxillofacial Surgery, 2022 The transcription factor tumour protein 63, encoded by the TP63 gene, is a regulator of epidermal development. Heterozygous mutations in TP63 cause a variety of human ectodermal dysplasia disorders, including ankyloblepharon-ectodermal defects-cleft lip ...
Yosuke Harazono +7 more
doaj +1 more source