Results 121 to 130 of about 28,276 (232)
Applied Linguistics, sociolinguistics and world Englishes
World Englishes, EarlyView.Abstract The world Englishes perspective, especially as expressed within Kachru's formulation of the Inner, Outer and Expanding Circles of Englishes, provides a flexible and coherent model of the historical spread of English. While the model has had a profound influence on various subfields of applied linguistics, variationist sociolinguistics ...
Andrew Moody
wiley +1 more source
Myotonic Mutations of Nav1.4 Located At EF Hand-Like Motif in C-Terminus Impair Fast Inactivation [PDF]
Biophysical Journal, 2020 Riho Horie +7 more
openaire +1 more source
TMEM16A channel signalling microdomains in the regulation of vascular function
The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley +1 more source
A Novel Ca2+ Binding β Hairpin Loop Better Resembles Integrin Sequence Motifs Than the EF Hand [PDF]
Cell, 2000 Springer, Timothy A +2 more
openaire +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend A sudden decrease in total peripheral resistance (TPR), as observed during vasovagal syncope, leads to a reduction in aortic systolic pressure (AO pressure) and afterload. In healthy individuals, the consequent decrease in left ventricular systolic pressure (LV pressure) lowers stroke work and myocardial energy expenditure.
Martin Dvoulety, Michal Sitina
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley +1 more source
Repairing Errors With Elaborative Feedback in Computerised Learning Environments
Journal of Computer Assisted Learning, Volume 42, Issue 2, April 2026.ABSTRACT Background Although automatic elaborative feedback (EF) is effective for teaching conceptual learning in science, there is insufficient evidence on how to adapt it in computer‐based question‐answering activities. Objectives This study aims to examine how we can make automatic EF more effective and tailored according to the knowledge revision ...
Tomás Martínez +3 more
wiley +1 more source
ChemistryOpen, Volume 15, Issue 4, April 2026.Perovskite oxides offer exceptional structural flexibility, enabling precise tuning of composition and electronic structure. This review connects these design parameters to both adsorbate‐ and lattice‐oxygen‐mediated OER pathways, highlighting the promise of rationally engineered perovskites as high‐performance electrocatalysts for alkaline water ...
Mikey Jones +6 more
wiley +1 more source
Protein Science, Volume 35, Issue 4, April 2026.Abstract Shwachman‐Diamond syndrome (SDS) is a rare genetic disorder characterized by pancreatic insufficiency and neutropenia. While most cases are linked to mutations in the SBDS gene, some involve mutations in the GTPase EFL1. This protein works with SBDS to release the anti‐association factor eIF6 from the 60S ribosomal subunit during ribosome ...
Jonathan A. Zúñiga‐Domínguez +6 more
wiley +1 more source