Results 21 to 30 of about 28,276 (232)
Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance [PDF]
Nature Medicine, 2013 EF-hand proteins are ubiquitous in cell signaling. Parvalbumin (Parv), the archetypal EF-hand protein, is a high-affinity Ca(2+) buffer in many biological systems. Given the centrality of Ca(2+) signaling in health and disease, EF-hand motifs designed to have new biological activities may have widespread utility.
Wang, Wang +10 more
openaire +2 more sources
Frontiers in Plant Science, 2022 Calmodulin (CaM) and calmodulin-like (CML) proteins are Ca2+ relays and play diverse and multiple roles in plant growth, development and stress responses. However, CaM/CML gene family has not been identified in barley (Hordeum vulgare).
Kangfeng Cai +9 more
doaj +1 more source
In silico prediction and analysis of Caenorhabditis EF-hand containing proteins. [PDF]
PLoS ONE, 2012 Calcium (Ca⁺²) is a ubiquitous messenger in eukaryotes including Caenorhabditis. Ca⁺²-mediated signalling processes are usually carried out through well characterized proteins like calmodulin (CaM) and other Ca⁺² binding proteins (CaBP).
Manish Kumar +4 more
doaj +1 more source
Structure of Ca2+-binding protein-6 from Entamoeba histolytica and its involvement in trophozoite proliferation regulation. [PDF]
PLoS Pathogens, 2017 Cell cycle of Entamoeba histolytica, the etiological agent of amoebiasis, follows a novel pathway, which includes nuclear division without the nuclear membrane disassembly. We report a nuclear localized Ca2+-binding protein from E.
Deepshikha Verma +4 more
doaj +1 more source
Biomolecules, 2022 Parvalbumin (PA) is a small, acidic, mostly cytosolic Ca2+-binding protein of the EF-hand superfamily. Structural and physical properties of PA are well studied but recently two highly conserved structural motifs consisting of three amino acids each ...
Eugene A. Permyakov, Vladimir N. Uversky
doaj +1 more source
Calcium affinity of human α-actinin 1 [PDF]
PeerJ, 2015 Due to alternative splicing, the human ACTN1 gene codes for three different transcripts of α-actinin; one isoform that is expressed only in the brain and two with a more general expression pattern.
Lars Backman
doaj +2 more sources
BMC Plant Biology, 2007 Background A wide range of stimuli evoke rapid and transient increases in [Ca2+]cyt in plant cells which are transmitted by protein sensors that contain EF-hand motifs. Here, a group of Oryza sativa L.
Buaboocha Teerapong +1 more
doaj +1 more source
A Medicago truncatula EF-hand family gene, MtCaMP1, is involved in drought and salt stress tolerance. [PDF]
PLoS ONE, 2013 BACKGROUND: Calcium-binding proteins that contain EF-hand motifs have been reported to play important roles in transduction of signals associated with biotic and abiotic stresses.
Tian-Zuo Wang +4 more
doaj +1 more source
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source