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Synthesis and application of a molecularly imprinted polymer in selective solid-phase extraction of efavirenz from water.

Water Science and Technology, 2019
Efavirenz is one of the antiretroviral drugs widely used to treat the human immunodeficiency virus. Antiretroviral drugs have been found to be present in surface water and wastewater.
Sinothando P Mtolo, P. Mahlambi, L. Madikizela +2 more
semanticscholar +1 more source

Doravirine dose Selection and 96-Week Safety and Efficacy versus Efavirenz in Antiretroviral Therapy-Naive Adults with HIV-1 Infection in a Phase IIb Trial

Antiviral Therapy, 2019
Background The safety and efficacy of doravirine were compared with that of efavirenz as initial treatment of adults living with HIV-1 infection (NCT01632345).
J. Gatell +20 more
semanticscholar +1 more source

Meta-analysis of the effect of CYP2B6, CYP2A6, UGT2B7 and CAR polymorphisms on efavirenz plasma concentrations.

Journal of Antimicrobial Chemotherapy, 2019
BACKGROUND Efavirenz primary metabolism is catalysed by CYP2B6 with minor involvement of CYP2A6. Subsequently, phase I metabolites are conjugated by UGT2B7, and constitutive androstane receptor (CAR) has been shown to transcriptionally regulate many ...
P. Ayuso, M. Neary, J. Chiong, A. Owen
semanticscholar +1 more source

Efavirenz