Results 151 to 160 of about 35,779,649 (289)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Land use alters cross-ecosystem transfer of high value fatty acids by aquatic insects
Environmental Sciences EuropeBackground Many aquatic insects emerge as adults from water bodies to complete parts of their life cycle in terrestrial ecosystems and are potential prey for riparian predators.
Katharina Ohler +6 more
doaj +1 more source
Simulation-Based Statistical Analysis of the Bullwhip Effect in Supply Chains
The paper proposes both statistical and simulation-based analysis and evaluation of the bullwhip effect in supply chains. The demand distortion, called the bullwhip effect, is considered as an important characteristic of supply chain operation stability.
Petuhova, Jūlija +2 more
core
Support for “Islamic State” in Indonesian prisons [PDF]
, 2015 This report examines how alliances for and against the "Islamic State" developed among inmates in Indonesian prisons. Introduction A study of networks in Indonesian prisons that support the Islamic State (IS) suggests that relatively simple ...
Institute for Policy Analysis of Conflict
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Preventive Behaviors of COVID-19 in the Iranian Adult Population during the Pandemic: The Integrated Effect of the Health Belief Model and the Planned Behavior Intention Using Causal Path Analysis [PDF]
Caspian Journal of Internal MedicineBackground: This study aimed to investigate the integration of the health belief model (HBM) and the theory of intention to plan preventive behavior for COVID-19 during the pandemic. Methods: In a cross-sectional study, a sample of 480 adult participants
Erfaneh Hajian-Tilaki +2 more
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source