Frontiers in Psychology, 2018 Introduction: Publications arguing against the null hypothesis significance testing (NHST) procedure and in favor of good statistical practices have increased. The most frequently mentioned alternatives to NHST are effect size statistics (ES), confidence
Laura Badenes-Ribera +4 more
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
International Journal of Integrated Care, 2002 This paper aims to identify problems in estimating and the interpretation of the magnitude of intervention-related change over time or responsiveness assessed with health outcome measures.
Berrie Middel, Eric van Sonderen
doaj
Clinical Effect of Tibial Plateau Leveling Osteotomy Compared to Lateral Fabellar Suture in Dogs
Veterinary Evidence, 2016 Objective: This manuscript used evidence based statistical methods that estimate clinical treatment effect rather than whether groups were statistically different.Background: The previously published blinded, randomised, controlled clinical trial ...
Wanda J Gordon-Evans
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Effect of Element Size in Random Finite Element Analysis for Effective Young’s Modulus [PDF]
, 2016 Jianye Ching, Yu-Gang Hu
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Effect of manganese doping on the size effect of lead zirconate titanate thin films and the extrinsic nature of ‘dead layers’ [PDF]
, 2010 X J Lou, J Wang
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Effect of Applying Time-Varying Load on The Optimal Location and Size of Fixed and Switched Capacitors on Radial Feeder with Laterals.(Dept.E) [PDF]
, 2021 K. Shebl
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source