Results 131 to 140 of about 4,692,305 (307)

Assessment of Vibrational Non-Equilibrium Effect on Detonation Cell Size

, 2017
To resolve the discrepancy between the numerical detonation cell size and experimental observations simulations are conducted with a detailed thermochemical reaction model for a premixed argon-diluted hydrogen-oxygen mixture. Four different scenarios are
Wen CH, 张德良, Wen, CY (reprint author), Hong Kong Polytech Univ, Dept Mech Engn, Kowloon, Hong Kong, Peoples R China., Shen H, Shi LS, Zhang P   +5 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The effects of GenAI on learning performance: A meta-analysis study

Educational Technology & Society
Artificial Intelligence (AI) has become increasingly prevalent in education, and Generative AI (GenAI) has emerged as a new concept in AI technology. Educators continue to debate the advantages and disadvantages of GenAI in education.
Seyfullah Gökoğlu and Fatih Erdoğdu
doaj   +1 more source

Teacher experience and the class size effect - experimental evidence [PDF]

We analyze teacher experience as a moderating factor for the effect of class size reduction on student achievement in the early grades using data from the Tennessee STAR experiment with random assignment of teachers and students to classes of different ...
Mueller, Steffen
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Is optimization an opportunity ? an assessment of the impact of class size and school size on the performance of Ukrainian secondary schools [PDF]

Using a rich data set of almost the entire population of Ukrainian secondary schools, the authors estimate the effect of school size and class size on the performance of secondary schools on Ukraine's External Independent Test.
Alonso, Juan Diego, Coupe, Tom, Olefir, Anna   +2 more
core   +2 more sources

Micrometre-scale plasticity size effects in metals and ceramics: theory and experiment.

, 2009
PhDThis thesis comprises studies of size effects in the plasticity of metals and ceramics at length scales of the order of micrometres and includes both experimental work and theoretical development. Experimental results are presented for foil flexure
Zhu, Tingting
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Birth Order Matters: The Effect of Family Size and Birth Order on Educational Attainment [PDF]

We use unique retrospective family background data from the 2003 wave of the British Household Panel Survey to explore the degree to which family size and birth order affect a child’s subsequent educational attainment. Theory suggests a trade off between
Hiau Joo Kee, Alison Booth
core