Results 151 to 160 of about 10,745,166 (286)

ML-MAGES enables multivariate genetic association analyses with genes and effect size shrinkage. [PDF]

Genome Res
Liu X, Crawford L, Ramachandran S.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Impacts of DIF Item Balance and Effect Size Incorporation With the Rasch Tree. [PDF]

Educ Psychol Meas
Asamoah NAB, Turner RC, Lo WJ, Crawford BL, Jozkowski KN.   +4 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Frequentist, Bayesian Analysis and Complementary Statistical Tools for Geriatric and Rehabilitation Fields: Are Traditional Null-Hypothesis Significance Testing Methods Sufficient?

Clinical Interventions in Aging
Dahan da Cunha Nascimento,1,* Nicholas Rolnick,2,* Isabella da Silva Almeida,3,* Gerson Cipriano Junior,4,* João Luiz Durigan3,* 1Physical Education Department, Universidade Católica de Brasília, Brasília, DF, Brazil; 2The Human ...
Nascimento DDC, Rolnick N, da Silva Almeida I, Cipriano Junior G, Durigan JL   +4 more
doaj  

Under my umbrella: Rating scales obscure statistical power and effect size heterogeneity. [PDF]

Behav Res Methods
Fünderich JH, Beinhauer LJ, Renkewitz F.   +2 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Cardiopulmonary exercise testing after cardiac resynchronization therapy: unit harmonization and effect-size methods require clearer reporting. [PDF]

Eur Heart J Open
Majeed S, Tu J.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Effect size and event rate estimation in neurocritical care randomised clinical trials: a protocol for a systematic review. [PDF]

BMJ Open
Shrestha GS, Kitisin N, Talbot P, Linke N, Taylor JD, Battistuzzo CR, Serpa Neto A, Higgins A, Jeffcote T, Cooper DJ, Udy AA.   +10 more
europepmc   +1 more source