Results 141 to 150 of about 24,937,001 (335)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Lorentz invariance of effective strings

, 1992
Starting from a Poincar\'e invariant field theory of a real scalar field with interactions governed by a double-well potential in 2+1 dimensions, the Lorentz representation induced on the collective coordinates describing low-energy excitations about an ...
Bardeen, Bardeen, Christ, Diehl, DiGiacomo, Frampton, Gervais, Gervais, Gildener, Hansson, Hughes, J.D. Cohn, Lin, Lüscher, Nielsen, Polchinski, Tinkham, Vipul Periwal, Volkov, Wallace   +19 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Effective description of axion defects

, 1993
Axion strings and domain walls exhibit a number of novel effects in the presence of gauge fields, in particular the electromagnetic field. It is shown how these effects are reproduced in a model of Nambu-Goto-type strings and open or closed membranes ...
Callan, Callan, Callan, Deser, Deser, Dirac, Dixon, Duff, Duff, Duff, Duff, Horowitz, Kallosh, Kogan, Lee, Lee, Naculich, Nepomechie, Nepomechie, Nicolai, P.K. Townsend,, Schwarz, Sikivie, Stone, Wilczek, Witten, Witten   +26 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

PERSPECTIVES ON SKILLS EFFICIENCY OF TRAINERS AND MANAGEMENT OF TRAINING TOWARDS EFFECTIVE TRAINING

International Journal of Social and Educational Innovation
The purpose of this research was to investigate the characteristics that impact in-service competence trainers to provide effective training in the South African Police Service (SAPS). To find the 500 respondents, this study used a quantitative strategy
Mmabatho Portia APHANE, Moitsadi ZITHA, Jacob Tseko MOFOKENG, Lerato MOFOKENG   +3 more
doaj  

Effective equations in quantum cosmology

, 2000
We develop a general framework for effective equations of expectation values in quantum cosmology and pose for them the quantum Cauchy problem with no-boundary and tunneling wavefunctions.
A.O. Barvinsky, Allen, Anderegg, Bahcall, Bardeen, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Barvinsky, Boisseau, Caldwell, D.V. Nesterov, Fakir, Fakir, Garriga, Garriga, Gratton, Guth, Halliwell, Hartle, Hawking, Hawking, Hawking, Hawking, Laflamme, Linde, Linde, Linde, Linde, Mukhanov, Polarski, Rubakov, Salopek, Smoot, Spokoiny, Strukov, Strukov, Vachaspati, Vilenkin, Vilenkin, Vilenkin, Vilenkin, Vilenkin, Zeldovich   +55 more
core   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Understanding the tumor immune microenvironment (TIME) for effective therapy

Nature Medicine, 2018
M. Binnewies, Edward W. Roberts, K. Kersten, Vincent Chan, Douglas Fearon, M. Merad, L. Coussens, D. Gabrilovich, Suzanne Ostrand-Rosenberg, Suzanne Ostrand-Rosenberg, C. Hedrick, R. Vonderheide, M. Pittet, R. Jain, W. Zou, T. Howcroft, E. Woodhouse, R. Weinberg, M. Krummel   +18 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source