Results 101 to 110 of about 25,629,046 (344)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Occurrence of Erosion-Effective Rain in the Brno Area

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016
Due to the growing awareness of the extent of degradation of agricultural soils as a result of water erosion, increased attention is paid to the establishing of effective erosion control measures based on reliable and timely input data.
Silvie Kozlovská, František Toman
doaj   +1 more source

Effective Management Of Parking Area

open access: yesInternational Journal of Engineering and Advanced Technology, 2019
When a car enters the parking area, it takes so much time to find the free slot to park. On the other hand, all the paid parking area owners suffer from handling congestion inside the parking area. They are spending huge amount as a salary for their employees to manage the parking area.
Suguna. M   +3 more
openaire   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Geometric effects in the effective-mass theory and topological optical superlattices

open access: yes, 2018
Cold atoms tailored by an optical lattice have become a fascinating arena for simulating quantum physics. In this area, one important and challenging problem is creating effective spin-orbit coupling (SOC), especially for fashioning a cold atomic gas ...
Feng, Ji, Li, Chao-Kai, Niu, Qian
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Distant objects detected visually with optical filters [PDF]

open access: yes, 1965
Fluorescent coating aids visual daylight detection and identification of distant objects. An object appears as a blinking light when the area is alternately scanned with transmitting and obscuring filters.

core   +1 more source

Effective area measurement of few-mode fiber using far field scan technique with Hankel transform generalized for circularly-asymmetric mode.

open access: yesOptics Express, 2016
We report on a measurement method for the effective area of the few-mode fiber. We derived a transform equation between a near-field pattern and a far-field pattern generalized for circularly-asymmetric higher-order modes of a cylindrical core, and ...
T. Hayashi   +8 more
semanticscholar   +1 more source

Large-N limit of the two-dimensoinal Yang-Mills theory on surfaces with boundaries

open access: yes, 2004
The large-N limit of the two-dimensional U$(N)$ Yang-Mills theory on an arbitrary orientable compact surface with boundaries is studied. It is shown that if the holonomies of the gauge field on boundaries are near the identity, then the critical behavior
Aghamohammadi   +25 more
core   +1 more source

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