Results 121 to 130 of about 2,617,588 (314)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Detector Response Matrices, Effective Areas, and Flash-Effective Areas for Radiation Detectors
A Detector Response Matrix (DRM) is a discrete representation of an instrument's Detector Response Function (DRF), which quantifies how many discrete energy depositions occur in a detector volume for a given distribution of particles incident on the detector.
Gregory Bowers +9 more
openaire +3 more sources
, 2018 Penelitian ini bertujuan untuk melihat hubungan penyesalan pasca pembelian dengan intensi membeli kembali pada mahasiswi Psikologi di Universitas Medan Area. Sampel dalam penelitian ini adalah mahasiswi Fakultas Psikologi Universitas Medan Area Kampus II
Baba, Andini Mariko
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Effective area of photonic crystal fibers
Optics Express, 2002 We consider the effective area A_eff of photonic crystal fibers (PCFs) with a triangular air-hole lattice in the cladding. It is first of all an important quantity in the context of non-linearities, but it also has connections to leakage loss, macro-bending loss, and numerical aperture.
openaire +3 more sources
, 2018 Penelitian ini bertujuan untuk mengetahui hubungan antara self-efficacy dengan problem solving dalam mengerjakan tugas akhir mahasiswa Fakultas Psikologi Universitas Medan Area. Pendekatan penelitian yang digunakan adalah pendekatan kuantitatif dengan
Septiani, Rahayu
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source