Results 131 to 140 of about 2,617,588 (314)

Implementation of Makassar City Coastal Area Protected Area Policy

open access: yes
Coastal areas are dynamic areas with interactions between land and sea, which exposes complex challenges in integrated management. Law No. 1 of 2014 on the management of coastal areas and small islands in Indonesia is a step to increase state authority ...
Fatmawati, Fatmawati   +4 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The Relationship between Hedonic Lifestyle and Consumptive Behavior in Management Study Program Students, Faculty of Economics and Business, University of Medan Area Stambuk 2019

open access: yes, 2023
81 HalamanPenelitian ini bertujuan untuk mengetahui hubungan antara gaya hidup hedonis dengan perilaku konsumtif mahasiswi Prodi Manajemen Fakultas Ekonomi dan Bisnis Universitas Medan Area Stambuk 2019.
Utami, Syawitri
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Determinants of the euro real effective exchange rate: a BEER/PEER approach [PDF]

open access: yes
This paper presents an empirical analysis of the medium-term determinants of the euro effective exchange rate. The empirical analysis builds on synthetic quarterly data from 1975 to 1998, and derives a Behavioural Equilibrium Exchange Rate (BEER) and a ...
Bernd Schnatz   +2 more
core   +2 more sources

The causes of area effects [PDF]

open access: yesHeredity, 1963
A J Cain, J D Currey
openaire   +1 more source

Labour productivity developments in the euro area [PDF]

open access: yes
This paper provides a description and a discussion of some important aspects relating to recent productivity developments in the euro area. Following decades of stronger gains in the euro area than in the US, labour productivity growth has fallen behind ...
Jarkko Turunen   +3 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Analysis of radiation risk to patients from intra-operative use of the mobile X-ray system (C-arm)

open access: yesJournal of Research in Medical Sciences, 2015
Background: The aim of this study was to investigate clinical applications of mobile C-arms and consequent radiation risk, to increase medical attention on radiation protection, and to provide basic data for safe radiation use in the operating room ...
Yang-Sub Lee   +3 more
doaj  

Home - About - Disclaimer - Privacy