Results 151 to 160 of about 2,617,588 (314)

Optimal utilization of classroom space and course offerings at Milwaukee Area Technical College South Campus [PDF]

, 2000
Plan BThe purpose of this study was to analyze the scheduling of afternoon courses at the Milwaukee Area Technical College South Campus. It was also to help assist in planning optimal space utilization for both classroom and course scheduling.
Lechmaier, Catherine A.
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Effective Areas of Ships

The Journal of the Nautical Society of Japan, 1966
Y. Fujii, K. Tanaka, K. Watanabe, K. Yamada, M. Seki   +4 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Two-dimensional solid-state array detectors: A technique for in vivo dose verification in a variable effective area. [PDF]

J Appl Clin Med Phys, 2019
Utitsarn K, Biasi G, Stansook N, Alrowaili ZA, Petasecca M, Carolan M, Perevertaylo VL, Tomé WA, Kron T, Lerch MLF, Rosenfeld AB.   +10 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Ultra-low-loss and large-effective-area fiber for 100 Gbit/s and beyond 100 Gbit/s coherent long-haul terrestrial transmission systems. [PDF]

Sci Rep, 2019
Wang D, Li Y, Zhang D, Zhou H, Zhao Y, Wang L, Tang R, Zhao X, Zhang L, Wu J, Wang R, Luo J, Zhao W, Li H.   +13 more
europepmc   +1 more source

Output and inflation responses to credit shocks: are there threshold effects in the euro area? [PDF]

This paper investigates whether output and inflation respond asymmetrically to credit shocks in the euro area. The methodology, based on a non-linear VAR system, follows work by Balke (2000) for the US.
Calza, Alessandro, Sousa, João
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Density-dependent changes in effective area occupied for sea-bottom-associated marine fishes. [PDF]

Proc Biol Sci, 2016
Thorson JT, Rindorf A, Gao J, Hanselman DH, Winker H.   +4 more
europepmc   +1 more source