Results 121 to 130 of about 25,629,046 (344)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Structural Design and Verification of an Effective-Area Measurement Device Detection System. [PDF]
Sensors (Basel), 2023 Chen X, Yun Z, You T, Quan X.
europepmc +1 more source
Fuselage design for a specified Mach-sliced area distribution [PDF]
A procedure for designing a fuselage having a prescribed effective area distribution computed from -90 deg Mach slices is described. This type of calculation is an essential tool in designing a complete configuration with an effective area distribution ...
Adams, Mary S., Barger, Raymond L.
core +1 more source
Gravitational Wilson Loop in Discrete Quantum Gravity
, 2011 Results for the gravitational Wilson loop, in particular the area law for large loops in the strong coupling region, and the argument for an effective positive cosmological constant discussed in a previous paper, are extended to other proposed theories ...
C. Itzykson +7 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Planning of Medical Flexible Needle Motion in Effective Area of Clinical Puncture. [PDF]
Sensors (Basel), 2023 Feng S, Feng S, Wang S, Jiang W, Gao X.
europepmc +1 more source
, 2016 Adequate macrotexture characterization is an essential objective for transportation practitioners because primary pavement surface characteristics like friction, tire–pavement noise, splash and spray, and rolling resistance are significantly influenced ...
Daniel E. Mogrovejo +4 more
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Analysis of Shear Lag in Steel Angle Connectors [PDF]
, 2013 Previous research has found an empirically based method for calculating the effective net area defined by stress distributions created by tensile loads in steel connections.
Sawyer, Benjamin
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source