Results 141 to 150 of about 791,939 (337)

The value of spectral CT quantitative parameters in predicting Ki-67 level in ovarian cancer

Frontiers in Oncology
ObjectiveThe objective of this study is to evaluate the predictive value of quantitative parameters from spectral CT for Ki-67 expression in ovarian cancer (OC).MethodsSpectral CT imaging data from 39 patients with ovarian cancer by pathology ...
Siwen Pang, Meng Wu, Haijia Yu, Tiantian Ma, Jianhua Liu, Siwen Liu   +5 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Dual-Layer Spectral Detector Computed Tomography Quantitative Parameters: A Potential Tool for Lymph Node Activity Determination in Lymphoma Patients

Diagnostics
Dual-energy CT has shown promising results in determining tumor characteristics and treatment effectiveness through spectral data by assessing normalized iodine concentration (nIC), normalized effective atomic number (nZeff), normalized electron density (
Hebing Chen, Yuxiang Fang, Jin Gu, Peng Sun, Lian Yang, Feng Pan, Hongying Wu, Tianhe Ye   +7 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Structural and attenuation properties of rare-earth and barium oxide modified borate glasses for gamma ray protection

Open Chemistry
This research intends to investigate the B2O3–TiO2–BaO–ZnO–La2O3–Nd2O3 glass system’s radiation shielding characteristics at the Cs-137-, Co-60-, and Na-22-emitted energies.
Almuqrin Aljawhara H., Aloraini Dalal A., Sayyed M.I., Alwehaibi Maymunah   +3 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

CRYSTALLINE COMPOUNDS WITH TUNABLE EFFECTIVE ATOMIC NUMBER Z FOR GAMMA AND NEUTRON DETECTORS

, 2018
S. É. Sarkisov, V. V. Ryabchenkov, V. A. Yusim, Mihail Yu. Smetanin, Oleg K. Shaihatarov, Alexey S. Samonov   +5 more
openalex   +2 more sources

Effective Atomic Number of Lead Sodium Borate Glass Systems at 662 keV [PDF]

, 2011
A.
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Increasing the Number of Material Recognition Classes in Cargo Inspection Using the X-Ray Dual High-Energy Method

Computation
Issues related to increasing the number of material recognition classes in cargo inspection by the X-ray dual high-energy method through introducing a class of heavy organic materials that include basic explosives are considered.
Sergey Osipov, Sergei Chakhlov, Eugeny Usachev   +2 more
doaj   +1 more source