Results 121 to 130 of about 181,833 (294)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Impact of MoO3 on gamma radiation shielding performance of B2O3–TeO2–GeO2–MgO glasses: experimental investigation

Discover Materials
This study presents data on the gamma radiation shielding properties of differential compositions of molybdenum oxide (MoO₃) incorporated into borate-tellurite-magnesium glasses with a formula of B2O3–TeO2–GeO2–MgO. The borate-tellurite-magnesium glasses
M.I. Sayyed, Mohamed Y. Hanfi, Berivan F. Namaq, Laith Ahmed Najam, Taha Yaseen Wais, Abed Jawad Kadhim, Kawa M. Kaky, Sudha D. Kamath   +7 more
doaj   +1 more source

The value of spectral CT quantitative parameters in predicting Ki-67 level in ovarian cancer

Frontiers in Oncology
ObjectiveThe objective of this study is to evaluate the predictive value of quantitative parameters from spectral CT for Ki-67 expression in ovarian cancer (OC).MethodsSpectral CT imaging data from 39 patients with ovarian cancer by pathology ...
Siwen Pang, Meng Wu, Haijia Yu, Tiantian Ma, Jianhua Liu, Siwen Liu   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Dual-Layer Spectral Detector Computed Tomography Quantitative Parameters: A Potential Tool for Lymph Node Activity Determination in Lymphoma Patients

Diagnostics
Dual-energy CT has shown promising results in determining tumor characteristics and treatment effectiveness through spectral data by assessing normalized iodine concentration (nIC), normalized effective atomic number (nZeff), normalized electron density (
Hebing Chen, Yuxiang Fang, Jin Gu, Peng Sun, Lian Yang, Feng Pan, Hongying Wu, Tianhe Ye   +7 more
doaj   +1 more source

Characterization of the effective atomic number for first row transition elements by the ratio of coherent to compton scattering intensities obtained by wavelength dispersive X-ray fluorescence

, 2016
The effective atomic numbers of compounds of the first row transition elements were determined experimentally by a scattering method using wavelength dispersive X-ray fluorescence spectrometer.
COMERT, Esra, YILMAZ, Demet, BOYDAŞ, Elif   +2 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Practical method for experimental effective atomic number in the coherent to Compton scattering ratio

, 2006
A practical method of calculating Z(eff) was developed for the coherent to Compton scattering ratio and the method is applicable for any material with known weight percentages of different elements in the compound.
Icelli, O, Icelli, Orhan
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Structural and attenuation properties of rare-earth and barium oxide modified borate glasses for gamma ray protection

Open Chemistry
This research intends to investigate the B2O3–TiO2–BaO–ZnO–La2O3–Nd2O3 glass system’s radiation shielding characteristics at the Cs-137-, Co-60-, and Na-22-emitted energies.
Almuqrin Aljawhara H., Aloraini Dalal A., Sayyed M.I., Alwehaibi Maymunah   +3 more
doaj   +1 more source