Results 121 to 130 of about 14,777,258 (301)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
New method to determine effective atomic number of samples via external bremsstrahlung
, 2014 In the present investigation, the variation in the external bremsstrahlung (EB) intensity produced due to the beta particles emitted by the 90Sr-90Y source in the elements Al, Cu, Ag, Sn, and Pb as well as some lead compounds was studied as a function of
Manjunatha, M. V. +2 more
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Discover MaterialsThis study presents data on the gamma radiation shielding properties of differential compositions of molybdenum oxide (MoO₃) incorporated into borate-tellurite-magnesium glasses with a formula of B2O3–TeO2–GeO2–MgO. The borate-tellurite-magnesium glasses
M.I. Sayyed +7 more
doaj +1 more source
Atomic Energy Commission Report ABCC-00-59
, 1959 References to 193 publications of staff members of the Atomic Bomb Casualty Commission during 1947 through 1959 are listed in both English and Japanese.
Atomic Bomb Casualty Commission
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The value of spectral CT quantitative parameters in predicting Ki-67 level in ovarian cancer
Frontiers in OncologyObjectiveThe objective of this study is to evaluate the predictive value of quantitative parameters from spectral CT for Ki-67 expression in ovarian cancer (OC).MethodsSpectral CT imaging data from 39 patients with ovarian cancer by pathology ...
Siwen Pang +5 more
doaj +1 more source
, 2010 The effective atomic number, Z(eff), has been calculated for fatty acids and cysteine. It is shown that Z(eff) is a useful parameter for low-Z materials at any energy above 1 key. Absorption edges of medium-Z elements may complicate the energy dependence
Hanagodimath, S.M. +3 more
core +1 more source