AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT Images. [PDF]
Sensors (Basel), 2022 Son K, Kim D, Lee S.
europepmc +1 more source
, 2016 {"references": ["D.F. Jackson, D.J. Hakes. \"X-ray attenuation coefficients of elements and mixtures\" Phys. Report 70 (1981) 169-233.", "J H Hubbell and S M Seltzer, Report, \"Tables of X-ray mass attenuation coefficients from 1 keV to 20 MeV for elements Z=1 to Z=92. NISTIR-5632 (1995).", "Hine G.J.
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Image synthesis of effective atomic number images using a deep convolutional neural network-based generative adversarial network. [PDF]
Rep Pract Oncol Radiother, 2022 Kawahara D, Ozawa S, Saito A, Nagata Y.
europepmc +1 more source
Effect of an atom on a quantum guided field in a weakly driven fiber-Bragg-grating cavity
, 2010 We study the interaction of an atom with a quantum guided field in a weakly driven fiber-Bragg-grating (FBG) cavity. We present an effective Hamiltonian and derive the density-matrix equations for the combined atom-cavity system.
A. Othenos +9 more
core +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Superradiant Quantum Heat Engine
, 2015 Quantum physics revolutionized classical disciplines of mechanics, statistical physics, and electrodynamics. One branch of scientific knowledge however seems untouched: thermodynamics.
Hardal, Ali Ü. C. +1 more
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Quantitative lung perfusion blood volume using dual energy CT-based effective atomic number (Zeff ) imaging. [PDF]
Med Phys, 2021 Li K +5 more
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