Results 51 to 60 of about 1,556,303 (288)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
WHETHER THERE WILL BE AN EFFECT FROM EFFECTIVE CONTRACT IN THE SYSTEM OF HIGHER EDUCATION?
Высшее образование в России, 2017 The article addresses the issues concerning the implementing of effective contract in higher education institutions. The author analyzes this problem through a prism of possible increase of labor productivity of university teaching staff and adduces ...
G. N. KRAYNOV
doaj
The principles of the formation of personnel academic strategies in Belarus
Ekonomika Nauki, 2019 The article presents the results of a scientific study of the current state of the motivational component of academic workers in the Republic of Belarus. The trends of academic behavior of the faculty of Belarusian universities are determined.
N. V. Makovskaya
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
ON THE REFORMING OF NATIONAL HIGHER EDUCATION SYSTEM
Высшее образование в России, 2017 The article considers the main stages of the reform of the Russian higher education system. It discusses the reasons why the ongoing educational reforms have not led to an improvement in the quality of higher education.
V. S. SENASHENKO
doaj
Strategic Effects of Renegotiation-Proof Contracts
The B.E. Journal of Theoretical Economics, 2012 It is well known that non-renegotiable contracts with third parties may have an effect on the outcome of a strategic interaction and thus serve as a commitment device. We address this issue when contracts are renegotiable. More precisely, we analyze the equilibrium outcomes of two-stage games with renegotiation-proof third-party contracts in relation ...
Emanuele Gerratana, Levent Koçkesen
openaire +4 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective contract in higher school: the implementationpractice
Высшее образование в России, 2016 The article describes in detail the implementation practice of effective contract for faculty members of the university, from planning to the results of the effectiveness. The authors consider the structure of indices matrix for evaluation the efficiency
Sergey N. Postnikov, Alena V. Andrienko
doaj
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source