Results 71 to 80 of about 3,806,530 (289)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Searching for Semantic Distance Effects
Glossa PsycholinguisticsLanguage processing relies on memory. There exists a considerable body of literature on retrieval in sentence processing and, in particular, on cases involving recall of syntax-relevant information. There is no reason to doubt, however, that memory is involved in semantic aspects of language processing as well.
Winkowski, Jan +2 more
openaire +3 more sources
Tunable Casimir repulsion with three dimensional topological insulators
, 2011 In this Letter, we show that switching between repulsive and attractive Casimir forces by means of external tunable parameters could be realized with two topological insulator plates.
Adolfo G. Grushin +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Supporting Distance Learners: Making Practice More Effective
Journal of Open, Flexible and Distance Learning, 2015 This paper reports on a qualitative evaluation of the postgraduate courses offered by distance in one university department. The types and amount of support provided to students was evaluated and compared with Simpson’s (2008a) Proactive Motivational ...
Keryn Pratt
doaj +2 more sources
Faculty Attitudes about Distance Education [PDF]
IAFOR Journal of Education, 2014 In recent years, there has been a dramatic increase in distance learning in higher education. Given this, it is extremely important to understand faculty attitudes about distance education, not only because they can vary widely, but also because it is ...
Esther Smidt +4 more
doaj
A Discussion on the Effective Ventilation Distance in Dead-End Tunnels
Energies, 2019 Forcing ventilation is the most widely used system to remove noxious gases from a working face during tunnel construction. This system creates a region near the face (dead zone), in which ventilation takes place by natural diffusion, rather than being ...
Manuel García-Díaz +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source