FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Effect of Geographic Distance on Distance Education: An Empirical Study
The Journal of Educators Online, 2014 This study investigates the effect of geographic distance on students’ distance learning experience with the aim to provide tentative answers to a fundamental question – does geographic distance matter in distance education? Using educational outcome data collected from an online master’s program in Geographic Information Systems, this study calculates
Heng Luo +2 more
openaire +2 more sources
The effective distance and cooling rate of liquid nitrogen-based adjunctive cryotherapy for bone tumors ex vivo. [PDF]
J Chin Med Assoc, 2022 Chang YC +5 more
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Probing the Dark Universe with Gravitational Waves
UniverseGravitational waves (GWs) are expected to interact with dark energy and dark matter, affecting their propagation on cosmological scales. To model this interaction, we derive a gauge-invariant effective equation and action valid for all GW polarizations ...
Antonio Enea Romano
doaj +1 more source
Impact of human mobility and networking on spread of COVID-19 at the time of the 1st and 2nd epidemic waves in Japan: An effective distance approach. [PDF]
PLoS One, 2022 Nohara Y, Manabe T.
europepmc +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Towards a more effective model for distance education
E-learning and Education, 2014 What is the most effective model for academic distance education, given that drop-out numbers in traditional distance education institutions are too high and the demands from the various stakeholders are changing?
Rob Koper
doaj
Effective Distance between Aortic Valve and Conduction System Is an Independent Predictor of Persistent Left Bundle Branch Block during Transcatheter Aortic Valve Implantation. [PDF]
Medicina (Kaunas), 2021 Poels TT +8 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source