Results 81 to 90 of about 3,806,530 (289)

Redefining effective distance using multi-hop flows in urban mobility networks

open access: yesJournal of Physics: Complexity
Effective distance, a concept that redefines spatial connectivity by considering human mobility links rather than physical distance, has proven to be a powerful tool for predicting epidemic spread.
Mengning Wang   +7 more
doaj   +1 more source

Student Attitudes about Distance Education: Focusing on Context and Effective Practices. [PDF]

open access: yesIAFOR Journal of Education, 2014
There has been an unquestionable upsurge in distance education in recent years. Given this, it is extremely important to understand the experience of online courses from students’ perspectives.
Esther Smidt   +4 more
doaj  

Variational Truncated Wigner Approximation

open access: yes, 2013
In this paper we reconsider the notion of an optimal effective Hamiltonian for the semiclassical propagation of the Wigner distribution in phase space.
Brosens, Fons, Sels, Dries
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Effective formulas for the Carath�odory distance

open access: yesManuscripta Mathematica, 1988
The authors are interested in computing the Carathéodory pseudodistance \(c_ G(0,z)\) from the center 0 of a balanced (i.e., complete circular) domain of holomorphy G in \({\mathbb{C}}^ n\) to a point \(z\in G\). When G is convex these distances are given by the well-known formula \[ c_ G(0,z)=\tanh^{-1} \inf \{\lambda >0:\quad z\in \lambda G\}, \] but
Jarnicki, M., Pflug, P.
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

E-readiness of open and distance learning (ODL) facilitators: Implications for effective mediation

open access: yesPerspectives in Education, 2014
This article is a narrative report of the findings from the analysis of multicultural facilitators’ discourses on their e-readiness in the use of information and communication technologies (ICTs) affordances in open and distance learning (ODL) mediation
Jabulani Nyoni
doaj   +3 more sources

An Energy Trace Compression Method for Differential Power Analysis Attack

open access: yesIEEE Access, 2020
Differential power analysis attacks are the most commonly used means to break cryptographic devices within the side-channel attack technology. Since there is a lot of noise in the energy trace of cryptographic devices, a large number of energy traces are
Xiaomin Cai   +3 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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