Results 131 to 140 of about 12,005,894 (331)

The Impact of Weight-Based Penalties on Drug Purity and Consumption: A Theoretical Analysis [PDF]

open access: yes
This paper investigates the impact of an increase in law enforcement on the purity of illicit drugs and illicit drug consumption. The impact is explored under the assumption that dealer penalties increase in the weight of drugs sold (as stipulated by ...
Robert T. Burrus, Jr.
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Effective treatment with double filtration plasmapheresis (DEPP) and high dose intravenous gammaglobulin therapy in a pregnant systemic lupus erythematosus(SLE) patient.

open access: bronze, 1989
Motoki Toyama   +8 more
openalex   +2 more sources

Head and neck effective dose and quantitative assessment of image quality: a study to compare cone beam CT and multislice spiral CT.

open access: yesDento maxillo facial radiology, 2017
C. Nardi   +6 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Animal Models of Depression and Drug Delivery with Food as an Effective Dosing Method: Evidences from Studies with Celecoxib and Dicholine Succinate [PDF]

open access: hybrid, 2015
João Costa-Nunes   +9 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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