Results 121 to 130 of about 2,488,526 (298)

Analysis of natural uranium in groundwater of Kanchipuram district of Tamil Nadu, India

Radiation Protection and Environment
Groundwater serves as the primary source of drinking water in rural and urban India as well as in many regions worldwide. In this study, the levels of uranium were determined in groundwater samples collected from the Kanchipuram district using the ...
Suja Subramanian, Satyanarayan Bramha, Kothai Parthasarathy, R. Ravisankar, S. Chandrasekaran   +4 more
doaj   +1 more source

Radiation-induced lowered neurogenesis associated with shortened latency of inhibitory avoidance memory response [PDF]

, 2011
The neural system is less sensitive to radiation than other late-responding organs and tissues such as the kidney and lung. The generation of new neurons in the adult mammalian brain has been documented in several works.
Azami, N.S., Heidari, M., Jahanshahi, M., Khoshnazar, A.K.   +3 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Initial Evaluation of Exposure of Adult Residents in Dange-Shuni Local Government Area to Radioactive Cesium (Cs-137) through Ingestion

UMYU Scientifica Journal
Radioactive Cesium (137-Cs) is widely used in hospitals as a gamma source for calibrating medical radiotherapy devices used in cancer treatment.  It is also employed to calibrate radiation detection instruments.
Aminu Saidu, Sabiu B Muhammad, Sulaiman A Ogunsina, Usman Abubakar, Junaidu Aliyu, Muttaka Umar, Abdullahi M Ibrahim, Bashir Abdullahi, Musa A Wasagu, Ibrahim M Danmalam, Mukhtar Abdulkadir   +10 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Patient-specific Effective Dose Estimation from Dose–Length Product in Lung Computed Tomography Using Monte Carlo Simulation

Journal of Medical Signals and Sensors
Background: Computed tomography (CT) imaging has a large portion in the dose of patients from radiological procedures; therefore, accurate calculation of radiation risk estimation in this modality is inevitable.
Gholamreza Fallahmohammadi, Zeinab Kordzini Nodeh, Mohammad Mahdavi   +2 more
doaj   +1 more source

The Impact of Weight-Based Penalties on Drug Purity and Consumption: A Theoretical Analysis [PDF]

This paper investigates the impact of an increase in law enforcement on the purity of illicit drugs and illicit drug consumption. The impact is explored under the assumption that dealer penalties increase in the weight of drugs sold (as stipulated by ...
Robert T. Burrus, Jr.
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source