Results 1 to 10 of about 8,300,360 (253)

A standardized measurement-based approach to estimate modelled relative biological effectiveness for auditing carbon ion beams [PDF]

Physics and Imaging in Radiation Oncology
Background and purpose: Differences in dose delivered during carbon radiotherapy are due largely to variations in relative biological effectiveness (RBE), which can be calculated by several models.
Shannon Hartzell, Fada Guan, Paige Taylor, Phillip J. Taddei, Alfredo Mirandola, Giuseppe Magro, Mario Ciocca, Christine B. Peterson, Stephen Kry   +8 more
doaj   +2 more sources

Assessment of Tumor Relative Biological Effectiveness in Low-LET Proton Irradiation [PDF]

Biomedicines
Background/Objectives: Within the range of spread-out Bragg peak (SOBP), LET (linear energy transfer) gradually increases from proton beam entrance point toward the beam exit direction.
Ying-Chun Lin, Jiamin Mo, Yuan-Hao Lee
doaj   +2 more sources

Microdosimetric characterization of proton relative biological effectiveness in pancreatic ductal adenocarcinoma cell lines [PDF]

Frontiers in Oncology
PurposePancreatic ductal adenocarcinoma (PDAC) is among the most radioresistant malignancies. Proton therapy assumes a uniform relative biological effectiveness (RBE) of 1.1 regardless of radiation quality.
Tianyu Wang, Tianyu Wang, Yuting Li, Sabrina N. Campelo, Lawrence Bronk, Paige A. Taylor, Tara N. Fujimoto, Dadi Jiang, Albert C. Koong, Fada Guan   +9 more
doaj   +2 more sources

First theoretical determination of relative biological effectiveness of very high energy electrons [PDF]

Scientific Reports, 2021
Very high energy electrons (VHEEs, E > 70 MeV) present promising clinical advantages over conventional beams due to their increased range, improved penumbra and relative insensitivity to tissue heterogeneities.
Rachel Delorme, Thongchai A. M. Masilela, Camille Etoh, François Smekens, Yolanda Prezado   +4 more
doaj   +2 more sources

Mechanistic Modeling of the Relative Biological Effectiveness of Boron Neutron Capture Therapy [PDF]

Cells, 2020
Accurate dosimetry and determination of the biological effectiveness of boron neutron capture therapy (BNCT) is challenging because of the mix of different types and energies of radiation at the cellular and subcellular levels.
Seth W. Streitmatter, Robert D. Stewart, Gregory Moffitt, Tatjana Jevremovic   +3 more
doaj   +2 more sources

Evaluation of organ-specific relative biological effectiveness of proton therapy using radiation-induced pneumonitis as an endpoint [PDF]

Clinical and Translational Radiation Oncology
Background and purpose: Proton therapy has become widely used for non-small cell lung cancer (NSCLC) due to its ability to spare normal tissue. However, the commonly assumed relative biological effectiveness (RBE) of 1.1 may underestimate the therapy’s ...
Li Liao, Ting Xu, Mei Chen, Tingshi Su, Narayan Sahoo, Xiaorong Zhu, Steven J. Frank, Quynh-Nhu Nguyen, Zhongxing Liao, Xiaodong Zhang   +9 more
doaj   +2 more sources

Recommendations for reporting and evaluating proton therapy beyond dose and constant relative biological effectiveness [PDF]

Physics and Imaging in Radiation Oncology
Background and purpose: In proton therapy, a relative biological effectiveness (RBE) of 1.1 is used to convert proton dose into an equivalent photon dose.
Armin Lühr, Dirk Wagenaar, Daniëlle B.P. Eekers, Lars Glimelius, Steven J.M. Habraken, Semi Harrabi, Miranda C.A. Kramer, Ranald I. Mackay, Ana Vaniqui, Alexandru Dasu, Damien C. Weber   +10 more
doaj   +2 more sources

Calibration and evaluation of the relative biological effectiveness for carbon-ion radiotherapy in a new relative to a clinically applied treatment planning system [PDF]

Radiation Oncology, 2022
Background The study objective was to validate the relative biological effectiveness (RBE) in RayStation for carbon-ion radiotherapy (CIRT) using the Syngo treatment planning system as reference. Methods Local effect model I was established in RayStation
Weiwei Wang, Zhijie Huang, Wei Sun, Xufei Wang, Jingfang Zhao, Hao Shen   +5 more
doaj   +2 more sources

Relative Biological Effectiveness of High LET Particles on the Reproductive System and Fetal Development [PDF]

Life, 2020
During a space mission, astronauts are inevitably exposed to space radiation, mainly composed of the particles having high values of linear energy transfer (LET), such as protons, helium nuclei, and other heavier ions.
Bing Wang, Hiroshi Yasuda
doaj   +2 more sources

Biological effectiveness and relative biological effectiveness of ion beams for in-vitro cell irradiation. [PDF]

Cancer Sci, 2022
Li H.
europepmc   +2 more sources