Variable Relative Biological Effectiveness of Protons in the Rat Spinal Cord: Measurements and Comparison With Model Calculations [PDF]
Advances in Radiation OncologyPurpose: To determine the relative biological effectiveness (RBE) in the rat spinal cord after 6 fractions of protons as a function of linear energy transfer (LET) and dose.
Christin Glowa, PhD +11 more
doaj +2 more sources
Proton relative biological effectiveness (RBE): a multiscale problem. [PDF]
Br J Radiol, 2019 Proton radiotherapy is undergoing rapid expansion both within the UK and internationally, but significant challenges still need to be overcome if maximum benefit is to be realised from this technique. One major limitation is the persistent uncertainty in proton relative biological effectiveness (RBE).
Underwood TS, McMahon SJ.
europepmc +6 more sources
Mixed- and multi-relative biological effectiveness model simultaneous optimization in carbon ion radiotherapy: A proof-of-concept [PDF]
Physics and Imaging in Radiation OncologyBackground and purpose: In carbon ion radiotherapy (CIRT), different relative biological effectiveness (RBE) models have been used for calculating RBE-weighted dose (DRBE).
Aaron Paul Osburg +8 more
doaj +2 more sources
IEEE Access, 2021 We report the effects of gold nanoparticles (GNP) on the enhancement of the dose effect and double-strand break (DSB) induction for X-ray monoenergies (10 keV–2 MeV).
Ya-Yun Hsiao +3 more
doaj +1 more source
Iranian Journal of Public Health, 2021 Background: The present study aimed to provide an empirical theoretical basis for the psychological phenomena that occur among competing athletes. To this end, we utilized the actor and partner interdependence model (APIM) to analyze the self- and ...
Hyunwoo Kang, Seyong Jang
doaj +1 more source
The suitability of micronuclei as markers of relative biological effect [PDF]
Mutagenesis, 2022 Abstract Micronucleus (MN) formation is routinely used as a biodosimeter for radiation exposures and has historically been used as a measure of DNA damage in cells. Strongly correlating with dose, MN are also suggested to indicate radiation quality, differentiating between particle and photon irradiation.
Charlotte J Heaven +12 more
openaire +2 more sources
A Critical Review of LET-Based Intensity-Modulated Proton Therapy Plan Evaluation and Optimization for Head and Neck Cancer Management [PDF]
International Journal of Particle Therapy, 2021 In this review article, we review the 3 important aspects of linear-energy-transfer (LET) in intensity-modulated proton therapy (IMPT) for head and neck (H&N) cancer management.
Wei Deng, PhD +8 more
doaj +1 more source
Neutron exposures in human cells: bystander effect and relative biological effectiveness. [PDF]
PLoS ONE, 2014 Bystander effects have been observed repeatedly in mammalian cells following photon and alpha particle irradiation. However, few studies have been performed to investigate bystander effects arising from neutron irradiation. Here we asked whether neutrons
Isheeta Seth +5 more
doaj +1 more source
Applied Sciences, 2022 Experimental microdosimetry along with the microdosimetric kinetic (MK) model can be utilized to predict the biological effects of ions. To predict the relative biological effectiveness (RBE) of ions and the survival fraction (SF) of human salivary gland
Sung Hyun Lee +15 more
doaj +1 more source
Assessment of in vitro radiosensitivity parameters of breast cancer cells following exposure to radiotherapy hospital-based facilities [PDF]
Iranian Journal of Medical Physics, 2018 Introduction: The aim of the present study was to assess the radiosensitivity parameters for SK-BR-3 (SKBR3) breast cancer cells that could be implemented in the cutting-edge treatment planning systems (TPS) for accelerated partial-breast irradiation ...
Samaneh Babazadeh Toloti +4 more
doaj +1 more source