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Microdosimetry in BNCT [PDF]

open access: yesHealth and Technology
Precision Radiation Oncology, EarlyView.
Anna Selva, Anna Bianchi, Valeria Conte
exaly   +6 more sources

Microdosimetry for Hadron Therapy: A State of the Art of Detection Technology

open access: yesFrontiers in Physics, 2022
The interest in hadron therapy is growing fast thanks to the latest technological advances in accelerators and delivery technologies, to the development of more and more efficient and comprehensive treatment planning tools, and due to its increasing ...
Giuseppe Schettino, Gabriele Parisi
exaly   +3 more sources

A standardized measurement-based approach to estimate modelled relative biological effectiveness for auditing carbon ion beams [PDF]

open access: yesPhysics and Imaging in Radiation Oncology
Background and purpose: Differences in dose delivered during carbon radiotherapy are due largely to variations in relative biological effectiveness (RBE), which can be calculated by several models.
Shannon Hartzell   +8 more
doaj   +2 more sources

Calculation of alpha particle single-event spectra using a neural network [PDF]

open access: yesFrontiers in Oncology
IntroductionA neural network was trained to accurately predict the entire single-event specific energy spectra for use in alpha-particle microdosimetry calculations.MethodsThe network consisted of 4 inputs and 21 outputs and was trained on data ...
Layth Alkhani   +3 more
doaj   +2 more sources

Microdosimetric characterization of proton relative biological effectiveness in pancreatic ductal adenocarcinoma cell lines [PDF]

open access: yesFrontiers in Oncology
PurposePancreatic ductal adenocarcinoma (PDAC) is among the most radioresistant malignancies. Proton therapy assumes a uniform relative biological effectiveness (RBE) of 1.1 regardless of radiation quality.
Tianyu Wang   +9 more
doaj   +2 more sources

Multi-arrays of 3D cylindrical microdetectors for beam characterization and microdosimetry in proton therapy

open access: yesFrontiers in Physics, 2022
The present work shows the performance of two new large microdosimetry multi-array systems having two different configurations, namely, pixel and strip configurations.
Diana Bachiller-Perea   +8 more
doaj   +1 more source

Quantifying Radiosensitization of PSMA-Targeted Gold Nanoparticles on Prostate Cancer Cells at Megavoltage Radiation Energies by Monte Carlo Simulation and Local Effect Model

open access: yesPharmaceutics, 2022
Active targeting gold nanoparticles (AuNPs) are a very promising avenue for cancer treatment with many publications on AuNP mediated radiosensitization at kilovoltage (kV) photon energies.
Ryder M. Schmidt   +8 more
doaj   +1 more source

Overview of DISCOVER22 experiment in the framework of INFN-LNGS Cosmic Silence activity: challenges and improvements in underground radiobiology

open access: yesFrontiers in Physics, 2023
One of the most intriguing and still pending questions in radiobiology is to understand whether and how natural environmental background radiation has shaped Life over millions of years of evolution on Earth.
Patrizia Morciano   +42 more
doaj   +1 more source

Progress in 3D Silicon Radiation Detectors

open access: yesFrontiers in Physics, 2022
In the past few years, there has been an increasing interest toward 3D silicon radiation detectors. Owing to their unique architecture, 3D detectors provide a remarkable radiation hardness at relatively low bias voltage (hence low power dissipation ...
Gian-Franco Dalla Betta   +2 more
doaj   +1 more source

A Novel Hybrid Microdosimeter for Radiation Field Characterization Based on the Tissue Equivalent Proportional Counter Detector and Low Gain Avalanche Detectors Tracker: A Feasibility Study

open access: yesFrontiers in Physics, 2021
In microdosimetry, lineal energies y are calculated from energy depositions ϵ inside the microdosimeter divided by the mean chord length, whose value is based on geometrical assumptions on both the detector and the radiation field.
M. Missiaggia   +22 more
doaj   +1 more source

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